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When combination therapy is required for the management of hypertension, the commercially available verapamil er 240 mg tablets containing verapamil in fixed combination with trandolapril should not be used for initial therapy. Instead, dosage should first be adjusted by administering each drug separately.N Engl J Med. TheThe mechanism of the interaction between amiodarone and warfarin in humans. Clin Pharmacol Ther.

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