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Trade namesNolvadex, Genox, Tamifen, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa682414
Pregnancy categoryAU: B3 US: D (Evidence of risk)
Routes of administrationBy mouth
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ATC codeL02BA01 ( WHO )
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Pharmacokinetic data
Protein binding99%
MetabolismHepatic (CYP3A4, 2C9 and 2D6)
Elimination half-life5-7 days [2]
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Endometrial Cancer Risk Exaggerated Dr. Assikis pointed out that much of the concern over endometrial cancer and tamoxifen dates back to a 1993 case-control study based on data from the Yale-New Haven Tumor Registry. The authors concluded that endometrial cancers that develop after tamoxifen therapy are more likely to be high-grade, poor-prognosis tumors.Results are shown in Table tamoxifen and celexa.

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The polymorphic enzyme Tamoxifen and celexa is involved in the formation of endoxifen and 4-hydroxytamoxifen, and it is the key enzyme that catalyzes the formation of endoxifen from N-desmethyltamoxifen. Endoxifen concentrations may differ among patients because of various CYP2D6 genotypessee Pharmacogenomics.It should be noted that the responsible drivers for the poor survival of basal-like tumors still remain unclear.

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Then a statistically significant benefit exists. The Breast Cancer Prevention Trial BCPT, NSABP P-1 was a double-blind, randomized, placebo-controlled trial with a primary objective to determine whether 5 years of tamoxifen tamoxifen and flu vaccine 20 mg/day would reduce the incidence of invasive breast cancer in women at high risk for the disease see INDICATIONS AND USAGE Secondary objectives included an evaluation of the incidence of ischemic tamoxifen and flu vaccine disease; the effects on the incidence of bone fractures; and other events that might be associated with the use of tamoxifen, including: endometrial cancer, pulmonary embolus, deep-vein thrombosis, stroke, and cataract formation and surgery see In this trial, 13, 88 women of at least 35 years of age were randomized to receive either tamoxifen or placebo for five years.Introduction Isntrauterine insemination IUI is widely used as an empirical treatment for a large group of subfertile patients.

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The three most influential confounders of AMH tamoxifen and flu vaccine were age at clinic visit, cancer stage, and exposure to chemotherapy.the high-risk women who took tamoxifen citrate tablets got certain side effects at a higher rate than those who took a placebo. Some of these side effects can cause death.

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