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|Trade names||Protonix, others |
|License data||EU EMA: by INN, US FDA: Pantoprazole|
|Pregnancy category||AU: B3 US: B (No risk in non-human studies)|
|Routes of administration||By mouth and intravenous|
|Drug class||proton pump inhibitor|
|ATC code||A02BC02 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Elimination half-life||1-2 hours|
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To 200 mg/kg/day produced dose-related increases in the incidences of hepatocellular adenomas and carcinomas. In the thyroid gland, treatment at 200 mg/kg/day produced increased incidences of follicular cell adenomas and carcinomas for both male and female rats.he protonix kidney conditions are contraindicated protonix kidney this drug.
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In the thyroid gland, treatment at 200 mg/kg/day produced increased incidences of follicular cell adenomas and carcinomas for both male and female rats. In a 24-month protonix and kidney study, Fischer 344 rats were treated orally with doses of 5 to 50 mg/kg/day, approximately 1 to 10 times the recommended protonix and kidney dose based on body surface area.Your list includes two medicines belonging to the 'acid suppressant agents' category: Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication.
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The mechanism leading to the formation of gastric carcinoids by substituted benzimidazoles has been carefully investigated and allows the protonix and kidney that it is a secondary protonix and kidney to the massively elevated serum gastrin levels occurring in the rat during chronic high-dose treatment.
In the two-year rodent protonix and kidneys an increased number of liver tumours was observed in rats and in female mice and was interpreted as being due to pantoprazole's high metabolic rate in the liver.Patients treated with pantoprazole and warfarin or phenprocoumon may need to be monitored for increase in INR and prothrombin time.
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At 4 weeks of treatment there was an increase in mean gastrin levels of 7% 35% and 72% protonix kidney pretreatment values in the 10, 20, and 40 mg protonix kidney groups, respectively. A similar increase in serum gastrin levels was noted at the 8-week visit with mean increases of 3% 26% and 84% for the three Pantoprazole dose groups.Call your doctor for medical advice about side effects.
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