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The dose is not to exceed 16 mg a day. Adults: The total daily dose for adults should not exceed 0.Digestive System: Dryness of mouth, epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation, jaundice. Genitourinary: Urinary frequency, difficult urination, urinary retention, early menses.

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Organon Pharmaceuticals USA. October 2012. Retrieved 24 October 2013.This chemical travels throughout the body searching for specific histamine receptors targets on cells Once attached to the receptors, histamine will cause swelling, itchiness and other symptoms associated with an allergic response. There are two types of histamine receptors: H1 and H2. H1 receptors affect small blood vessels and smooth muscles.

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