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    Nsomnia 13. Frequency not reported: Emotional problems, transient emotional disturbances, behavioral changes, mania, nightmares, delusions, tension, anger, organic psychosis, dysphoria Postmarketing reports: Anxiety, depression, mood swings, panic attacks, confusion/confusional state, hallucinations, mefloquine tab 250mg, agitation, restlessness, psychotic/paranoid mefloquine tabs 250mg, suicidal ideation, suicide, attempted suicide, self-endangering behavior, bipolar disorder, psychotic disorder including delusional disorder, depersonalization, mania, schizophrenia/schizophreniform disorder paranoia, disturbance in attention Ref Common 1% to 10% Nausea, diarrhea, abdominal pain, mouth ulcers, vomiting Postmarketing reports: Nausea, vomiting, abdominal pain, loose stools/diarrhea, dyspepsia, pancreatitis Ref Encephalopathy of unknown etiology was reported during prophylactic use; however, the relationship to drug administration could not be established.Speich r, Haller A "Central anticholinergic syndrome with the antimalarial drug mefloquine.

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