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Levothyroxine sodium tablets should not be discontinued during pregnancy and hypothyroidism diagnosed during pregnancy should be promptly treated.1445.

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In: Wilson JD, Forster DW, Kronenberg HM, Larsen PR eds. Williams textbook of endocrinology.he FDA states that all where is mylan levothyroxine manufactured levothyroxine sodium preparations should be considered therapeutically inequivalent unless equivalence has been established and noted in FDA's Approved Drug Products with Therapeutic Equivalence Evaluations Orange Book Theoretically, such preparations can be used interchangeably, and in some cases, pharmacists may be able to substitute generic for proprietary brand preparations without notifying the prescriber.

However, because of the narrow therapeutic index of the drug, the American Thyroid Association ATA and the American Association of Clinical Endocrinologists AACE state that levothyroxine sodium preparations generally should not be used interchangeably.

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