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Hydroxychloroquine
Clinical data
Trade namesPlaquenil, others
AHFS/Drugs.comMonograph
MedlinePlusa601240
Pregnancy categoryAU: D US: C (Risk not ruled out)
Routes of administrationBy mouth (tablets)
ATC codeP01BA02 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityVariable (74% on average); T max = 2–4.5 hours
Protein binding45%
MetabolismLiver
Elimination half-life32–50 days
ExcretionMostly Kidney (23–25% as unchanged drug), also biliary (<10%)

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Most existing data about the prevalence of hydroxychloroquine retinal hydroxychloroquine chloroquine come from studies2, based primarily on short duration of use and on diagnosis hydroxychloroquine chloroquine an advanced stage of visible retinal damage. However, retinopathy can be detected much earlier by central visual field testing and modern techniques, such as spectral-domain optical coherence imaging hydroxychloroquine chloroquine 5 Because hydroxychloroquine distributes poorly in fatty tissues, it was suggested earlier7, and reinforced by current Hydroxychloroquine chloroquine Academy of Ophthalmology screening guidelines9 that dosage should be calculated by ideal body weight to reduce the theoretical risk of overdosing obese patients.have controlled pain much better with very low carb diet keeping weight down, staying away from gluten refined sugar or any type of aspartame.

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Rchdermatol. Epub 2011 Jul 18.00 embarazos que indican que hidroxicloroquina no produce malformaciones ni toxicidad fetal/neonatal. Los estudios realizados en animales son insuficientes en t rminos de toxicidad para la reproducci n.

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