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Clinical data
Pronunciation/ ˌ æ m ɪ ˈ t r ɪ p t ɪ l iː n / [1]
Trade namesElavil, others
License dataUS   FDA: Amitriptyline
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, intramuscular injection
Drug classTricyclic antidepressant (TCA)
ATC codeN06AA09 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding96% [2]
MetabolismLiver [2] (CYP2C9)
Elimination half-life10–50 hours [2]
ExcretionUrine [2]

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Amitriptyline synonymadepril, adtzimaia, amilavil, amilin, amiplin, amirol, amit, amitriptinova, amitriptylin, amitriptylini, amixide, amytril, amyzol, diapatol, elatrol, limbitryl, limbritol, maxivalet, minitran, nobritol, normaln, psiquium, qualitripitine, stelminal, teperin, trepiline, trip, tripta, triptafen, triptilin, triptizol, triptyl, tryptal, tryptin, tryptomer, uxen retard
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Reprints and PermissionsAbeyaratne, D. Liyanapathirana, C. Gamage, A. et al. Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest.Copyright 1996-2018 Cerner Multum, Inc.

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