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While the precise role of histamine in central vestibular processing is uncertain, there are data indicating that centrally acting antihistamines prevent motion sickness and reduce the severity of its symptoms even if taken after the onset of symptoms Takeda et al, 1989 All the antihistamines in general use for control of vertigo also have anticholinergic activity.

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Antiemetic effect may diminish with prolonged use.

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Ertigo apo dimenhydrinate 50mg the sensation of spinning or rocking, even when someone is at rest.Churchill Livingstone, Edinburgh, Symptoms and Subjective Handicaps in Patients with Dizziness. Otol Neurotol of betahistine on the vestibulo-ocular reflex: a double-blind placebo controlled study in patients with paroxysmal vertigo.

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